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ADIPEX-P (PHENTERMINE HCL): OVERDOSAGE

Manifestations of acute overdosage with Phentermine Hydrochloride include tremor, restlessness, hyperreflexia, rapid respiration, assaultiveness, confusion, hallucinations, panic states. Fatigue and depression usually follow the central stimulation.

Cardiovascular effects include hypertension or hypotension, arrhythmia, and circulatory collapse.

Gastrointestinal symptoms include vomiting, nausea, diarrhea and abdominal cramps.

Fatal poisoning usually terminates in convulsions and coma.

Management of acute Adipex-P (Phentermine HCl) capsules and tablets intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. Acidification of the urine increases phentermine excretion. Intravenous phentolamine (Regitine, CIBA) has been suggested for possible acute, severe hypertension, if this complicates Adipex-P (Phentermine) overdosage.



Adipex-P (Phentermine HCL) related pharmaceutical drugs and medications

Trade name of the drug Pharmaceutical forms and doses Companies
Wonlistat - Orlistat
  • Tablets; Oral; Orlistat 60 mg
  • Tablets; Oral; Orlistat 120 mg
  • Wonder Healthcare
  • Xtra
  • Tenuate and Tenuate Dospan overdosage - Diethylpropion Hydrochloride
  • Tablets, Extended Release; Oral; Diethylpropion Hydrochloride 75 mg
  • Sanofi-Aventis
  • Adcock Ingram


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